Luke Chang

Luke Chang

Luke Chang is a researcher in neuroscience and first author of a 2013 study of the insula using large-scale reverse inference.

Who they are

The work of Luke Chang reaches this site through the paper listed below. On this site the name is tied to Large-Scale Decoding, Reverse Inference.

Key papers

Chang, L. J., Yarkoni, T., Khaw, M. W., & Sanfey, A. G. (2013). Decoding the role of the insula in human cognition: Functional parcellation and large-scale reverse inference. Cerebral Cortex, 23(3), 739-749. What it reports: The study combined connectivity-based parcellation of the insula with large-scale meta-analytic decoding and supported three subregions, each linked to a distinct function.

Key ideas

Large-Scale Decoding: Using patterns of activity pooled from many studies to estimate which mental process an activation map reflects.

Reverse Inference: Reasoning from a measured pattern back to a feeling or mental state, which needs its own evidence.


Sources

  1. Chang, L. J., Yarkoni, T., Khaw, M. W., & Sanfey, A. G. (2013). Decoding the role of the insula in human cognition: Functional parcellation and large-scale reverse inference. Cerebral Cortex, 23(3), 739-749.