Xu Liu

Xu Liu

Xu Liu is a neuroscientist and first author of the 2012 study of optogenetic stimulation of a hippocampal engram.

Who they are

Xu Liu is a neuroscientist and first author of the 2012 study of optogenetic stimulation of a hippocampal engram. On this site the name is tied to Engram, Optogenetics.

Key papers

Liu, X., Ramirez, S., Pang, P. T., Puryear, C. B., Govindarajan, A., Deisseroth, K., & Tonegawa, S. (2012). Optogenetic stimulation of a hippocampal engram activates fear memory recall. Nature, 484(7394), 381-385.

Ramirez, S., Liu, X., Lin, P.-A., Suh, J., Pignatelli, M., Redondo, R. L., Ryan, T. J., & Tonegawa, S. (2013). Creating a false memory in the hippocampus. Science, 341(6144), 387-391.

Key ideas

Engram: The lasting physical change an experience leaves in a specific group of brain cells, whose reactivation brings the memory back.

Optogenetics: A method that makes chosen cells respond to light, used to switch tagged memory cells on in mice.

Sources

  1. Liu, X., Ramirez, S., Pang, P. T., Puryear, C. B., Govindarajan, A., Deisseroth, K., & Tonegawa, S. (2012). Optogenetic stimulation of a hippocampal engram activates fear memory recall. Nature, 484(7394), 381-385.
  2. Ramirez, S., Liu, X., Lin, P.-A., Suh, J., Pignatelli, M., Redondo, R. L., Ryan, T. J., & Tonegawa, S. (2013). Creating a false memory in the hippocampus. Science, 341(6144), 387-391.