Dissociable intrinsic connectivity networks for salience processing and executive control
Seeley and colleagues use task-free connectivity analyses to isolate two distinct brain networks that are usually coactivated during functional MRI tasks. They identify a salience network, anchored in the dorsal anterior cingulate and orbital frontoinsular cortices with strong links to subcortical and limbic structures, and an executive-control network linking dorsolateral frontal and parietal regions. The two networks show dissociable correlations with functions measured outside the scanner.
Seeley and colleagues use task-free connectivity analyses to isolate two distinct brain networks that are usually coactivated during functional MRI tasks. They identify a salience network, anchored in the dorsal anterior cingulate and orbital frontoinsular cortices with strong links to subcortical and limbic structures, and an executive-control network linking dorsolateral frontal and parietal regions. The two networks show dissociable correlations with functions measured outside the scanner.
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Seeley, W. W., Menon, V., Schatzberg, A. F., Keller, J., Glover, G. H., Kenna, H., Reiss, A. L., & Greicius, M. D. (2007). Dissociable intrinsic connectivity networks for salience processing and executive control. Journal of Neuroscience, 27(9), 2349-2356. doi:10.1523/JNEUROSCI.5587-06.2007